Advanced paternal age increases risk of bipolar disorder in offspring

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منابع مشابه

Advanced paternal age increases risk of bipolar disorder in offspring.

ED FROM Frans EM, Sandin S, Reichenberg A, et al. Advancing paternal age and bipolar disorder. Arch Gen Psychiatry 2008;65:1034–40. Correspondence to: Emma M Frans, MMedSc, Department of Medical Epidemiology and Biostatistics, Karolinksa Institute, PO Box 281, SE-171 77 Stockholm, Sweden; [email protected] Source of funding: None reported. c A table is published online only at http://ebmh.bmj.co...

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Advancing paternal age and bipolar disorder.

CONTEXT Advancing paternal age has been reported as a risk factor for neurodevelopmental disorders. OBJECTIVES To determine whether advanced paternal age is associated with an increased risk of BPD in the offspring and to assess if there was any difference in risk when analyzing patients with early-onset BPD separately. DESIGN A nationwide nested case-control study based on Swedish register...

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Paternal and maternal ages at conception and risk of bipolar affective disorder in their offspring.

BACKGROUND A consistent association between paternal age and their offspring's risk of schizophrenia has been observed, with no independent association with maternal age. The relationship of paternal and maternal ages with risk of bipolar affective disorders (BPAD) in the offspring is less clear. The present study aimed at testing the hypothesis that paternal age is associated with their offspr...

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Advanced paternal age increases the risk of schizophrenia and obsessive–compulsive disorder in a Chinese Han population

Using the Structured Clinical Interview for DSM-IV, patient and non-patient version (SCID-P/NP), this study investigated 351 patients with schizophrenia, 122 with obsessive-compulsive disorder (OCD), and 238 unrelated healthy volunteers in a Chinese Han population. The relative risks posed by advanced paternal age for schizophrenia and OCD in offspring were computed under logistic regression an...

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Paternal Age Alters Social Development in Offspring

OBJECTIVE Advanced paternal age (APA) at conception has been linked with autism and schizophrenia in offspring, neurodevelopmental disorders that affect social functioning. The current study explored the effects of paternal age on social development in the general population. METHOD We used multilevel growth modeling to investigate APA effects on socioemotional development from early childhoo...

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ژورنال

عنوان ژورنال: Evidence-Based Mental Health

سال: 2009

ISSN: 1362-0347

DOI: 10.1136/ebmh.12.2.59